Fast Delivery 82640-04-8 ManufacturerHot Sale Raloxifene hydrochloride

Raloxifene (LY156758, Keoxifene) HCl is a selective estrogen receptor receptor regulator (SERM) that inhibits the oxidation activity of cytoplasmic oxidase-catalyzed cytosine, with IC50 at 5.7 nM.

Raloxifene has been shown to be effective, non-competitive human liver aldehyde dehydrogenase catalytic sterols, vanilla aldehyde, and nicotine-δ'(5') - amine ion oxidation inhibitors, with Ki values of 0.87nM and 1.2nMand1.4nM, respectively. Raloxifene is also a non-competitive inhibitor that inhibits the compound reduction reaction of isohydroxyric acid catalyzed by aldehyde dehydrogenase, with a Ki value of 51nM. Raloxifene activates TGF beta 3 promoters as a complete agonist at nanomolar concentrations, and in transient transfection experiments, raloxifene inhibits the expression of estrogen response elements containing yolk progenitor promoters as pure estrogen antagonists.

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