Xi’an Salus Nutra Inc Established in 2015 and located in Hi-Tech industrial Zone in xi’an city, which is the most advanced area in northwest china . Salus Nutra is a professional company specialized in natural plant extracts, collagen and high technology chemical API field in scientific research, producing and marketing.

Our products are mainly used in healthcare supplement, chemicals ,pharmaceutical, cosmetics and food additives. We are also engaged in supplying customization OEM service to help customers choose their right ingredients and develop their broad markets .

Our factory is located in BaoJi ,shaanxi province, it coveries an area of 2000 acres and equips with 2 standard production workshops meet with State Health Standards ,meanwhile employs more than 500 people with well-educated, including undergraduate, Postgraduate and some technical persons with rich experience.

Salus is committed to supplying safe, pure and healthy products that meet the high expectations of our customers. Experienced and dedicated members of the Quality and food safety Department work to provide in-depth analyses, testing and monitoring of our products, during and after the manufacturing processes and ensure the quality and safety according to the highest standards.

We are based on the honest and mutual benefits, rely on the reliable quality and best after-sale service to make good reputations both online and offline. Now it shares a great popularities from the customers at overseas. Our primary goal aims to solve customer problems through research & development & technical service .

If you have any doubts or confusion, YES, Salus will present the exactly right answer.

78628-80-5 Terbinafine Hcl 

Product Name: Terbinafine
Purity: 98%min
Appearance: White crystalline powder
CAS No.: 91161-71-6
Molecular formula: C21H25N
Molecular weight: 291.43000

Terbinafine hydrochloride a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.   Terbinafine·HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis.   Additionally, Terbinafine has also been reported to suppress cell proliferation in vitro and in vivo through inhibition of DNA synthesis and apoptosis activation. It has also been noted that by pretreating of cells with a p21 specific antisense oligonucleotide the Terbinafine induced inhibition of cell growth can be reversed.

Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion ofsqualene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis.

1. Terbinafine is mainly effective on the dermatophyte group of fungi.

2. As a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals.
3. Oral 250-mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied. 
4. Terbinafine hydrochloride may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.